Landry-Guillain-Barre-Strohl syndrome | Paralysis

 

Landry-Guillain-Barre-Strohl syndrome, hereafter called Guillain-Barre syndrome, is a disorder of peripheral nerves, characterized by subacute (days to weeks) progression of motor-sensory dysfunction not associated with meningismus or fever. The syndrome was first described by Landry in 1859 and by Guillain, Barre, and Strohl in 1916. The diagnostic criteria developed by Asbury and Cornblath based on the pathophysiologic and morphologic understanding of Guillain-Barre syndrome, correspond to those of acute inflammatory demyelinating polyradiculoneuropathy (AIDP). There is increasing evidence that what is diagnosed as Guiltem-Barre" syndrome may include conditions originating from a variety of underlying pathogenic mechanisms. In the absence of wild virus-induced poliomyelitis, Guillain-Barre syndrome is the most common cause of AFP in many parts of the world, and it accounts for over 50 percent of AFP cases in both industrialized and developing countries. The annual incidence globally is 1-2 per 100,000 population; however, there are differences by region and ethnicity.